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Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal clone SP224, recombinant, expressed in proprietary host, affinity isolated antibody

ITEM#: 3042-SAB5500009100UL

MFR#: SAB5500009-100UL

Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase and it participates in the repair of DNA double-strand breaks. ATM is expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, spleen, thymus, testis

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Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase and it participates in the repair of DNA double-strand breaks. ATM is expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, spleen, thymus, testis, ovary, small intestine, colon and leukocytes. Increased ATM protein expression was reported in prostatic intraepithelial neoplasias (PINs) and some prostate cancer. ATM mutation has also been identified in mantle cell lymphoma, gastric cancer, lung adenocarcinoma, and breast cancer.
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Product Name Description Item# QTY
Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP242, affinity isolated antibody Androgen receptor (AR) is a receptor for the androgenic hormones testosterone or dihydrotestosterone and it is a member of the steroid superfamily of ligand-dependent transcription factors. In the absence of androgen, the unligated AR mainly locates 3042-SAB5500007100UL EA
Anti-Androgen Receptor antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP107, affinity isolated antibody The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. The expression of AR is reportedly inversely correlated with histologic grade, i.e., well differentiated prostate tumors show higher expressi 3042-SAB5500006100UL EA
Anti-C-TEN antibody, Rabbit monoclonal clone SP83, recombinant, expressed in proprietary host, affinity isolated antibody C-TEN/TNS4 links the focal adhesion and cell adhesion signaling to the actin cytoskeleton. It may be involved in cell survival and migration. The protein may be involved in cell migration, cartilage development and in linking signal transduction path 3042-SAB5500089100UL EA
Anti-CD25 antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP176, affinity isolated antibody Interleukin-2 receptor subunit alpha, also known as CD25, is a type I transmembrane protein and the alpha chain of the IL-2 receptor. CD25 and CD122 form a heterodimer to act as a high-affinity receptor for IL-2. CD25 is expressed on activated T cell 3042-SAB5500055100UL EA
Anti-SPINK1 antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP166, affinity isolated antibody Spink1 is a trypsin inhibitor secreted from pancreatic acinar cells into pancreatic juice. It prevents the trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Spink-1 is overexpressed in some prostate carci 3042-SAB5500177100UL EA
Anti-PTEN antibody, Rabbit monoclonal clone SP170, recombinant, expressed in proprietary host, affinity isolated antibody Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and a member in the PI3K/PTEN/AKT pathway. PTEN is a phosphatase with dual specificity to slow cell growth and antagonize t 3042-SAB5500168100UL EA
Anti-EGFR antibody, Rabbit monoclonal clone SP111, recombinant, expressed in proprietary host, affinity isolated antibody EGFR is a transmembrane tyrosine kinase that belongs to the HER/erbB protein family. Somatic mutations in the tyrosine kinase domain of EGFR are present in a subset of lung adenocarcinoma. Two types of mutations account for approximately 90% of mutan 3042-SAB5500098100UL EA
Anti-EGFR antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP84, affinity isolated antibody Epidermal Growth Factor Receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophag 3042-SAB5500096100UL EA
Anti-MSH6 antibody, Rabbit monoclonal clone SP93, recombinant, expressed in proprietary host, affinity isolated antibody Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predis 3042-SAB5500145100UL EA
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