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Anti-DENND6B antibody produced in rabbit Prestige Antibodies(R) Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2

ITEM#: 3042-HPA021653100UL

MFR#: HPA021653-100UL

DENND6B (DENN/MADD domain containing 6B) is a member of DENN (Differentially expressed in normal and neoplastic cells) domain protein family. It is located on chromosome 5. The members of this family consist of a C-terminal domain of 400-500 amino ac

DENND6B (DENN/MADD domain containing 6B) is a member of DENN (Differentially expressed in normal and neoplastic cells) domain protein family. It is located on chromosome 5. The members of this family consist of a C-terminal domain of 400-500 amino acids with two lobes, which can adhere to each other and Rab. It is also composed tripartite ′domains′ of u-DENN, c-DENN and d-DENN and N-terminal longin domain (LD) ββαβββαα fold. It shows Rab GEF activity in cell polarization, proliferation, and cell migration.