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Anti-PATE1 Antibody from rabbit, purified by affinity chromatography

ITEM#: 3042-ABC244

MFR#: ABC244

PATE1 is a secreted protein that is expressed exclusively in the prostate and testis and is up regulated in the prostate epithelial cells during cancer. Because of the extreme specificity of PATE1 expression it makes it a potential target for immunot

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PATE1 is a secreted protein that is expressed exclusively in the prostate and testis and is up regulated in the prostate epithelial cells during cancer. Because of the extreme specificity of PATE1 expression it makes it a potential target for immunotherapy in prostate cancer. PATE1 is the founding member of new syntenic loci in humans and mice that encode secreted proteins that have 10 cysteine residues. The PATE family has three-fingered protein/Ly-6/urokinase-type plasminogen activator receptor (uPAR) domains that shape three-fingered proteins (TFPs). Additional members include PATE-M, PATE-DJ, and PATE-B that are also expressed in prostate and testis and sperm. Related proteins, PATE-P and PATE-Q are expressed only in placenta. Research indicates that PATE proteins may have something to do with fertility and recent research showed that addition PATE-like genes were expressed in neuron-rich tissues and thus may have a role in neurological function or transmission.
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Product Name Description Item# QTY
Anti-PATE1 Antibody from rabbit, purified by affinity chromatography Prostate and testis expressed protein 1 (PATE1) is a secreted protein that, as the name suggests, is expressed exclusively in the prostate and testis. PATE1 is up regulated in the prostate epithelial cells during cancer, and its extreme specificity o 3042-ABC930 EA
Anti-WNK3 Antibody WNK3 is a serine-threonine protein kinase and expressed throughout the nephron, but most commonly at intercellular junctions. In its active state, it is a promoter of NKCC2 and NCC activity. The opposite is true of WNK3 when in an inactive state. WNK 3042-072262 EA
Anti-Sin3A Antibody Paired amphipathic helix protein Sin3a (UniProt Q60520; also known as Histone deacetylase complex subunit Sin3a, mSin3a, Transcriptional co-repressor Sin3a) is encoded by the Sin3A (also known as mSin3A, AW553200, Kiaa4126, mKIAA4126) gene (Gene ID 8 3042-06913I EA
Anti-SKI Antibody from rabbit, purified by affinity chromatography Ski oncogene (SKI) is also called Proto-oncogene c-Ski. Ski acts as a repressor of TGF-beta signaling. Ski is thought to be involved in terminal differentiation of skeletal muscle cells, but not in driving cells toward a myogenic lineage. 3042-ABE1070 EA
Anti-ST6GAL1 Antibody from rabbit, purified by affinity chromatography ST6GAL1, also known as Beta-galactoside alpha-2/ 6-sialyltransferase 1, or Alpha 2/ 6-ST 1, and encoded by the gene symbol ST6GAL1/ SIAT1, is a member of the glycosyltransferase 29 family. ST6GAL1 has been implied to play an important role in the tra 3042-ABC512 EA
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