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Anti-Phospho-gammaH2A.X-S139 antibody produced in rabbit

ITEM#: 3042-SAB5700329100UL

MFR#: SAB5700329-100UL

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of

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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
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Product Name Description Item# QTY
Anti-Phospho-gammaH2A.X-S2 antibody produced in rabbit Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of 3042-SAB5700434100UL EA
Anti-Phospho-MAP2K1-T286 antibody produced in rabbit The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration 3042-SAB5700312100UL EA
Anti-Phospho-GAP43-S41 antibody produced in rabbit The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effec 3042-SAB5700353100UL EA
Anti-Phospho-CRKL-Y207 antibody produced in rabbit This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosin 3042-SAB5700488100UL EA
Anti-Phospho-CRK-Y221 antibody produced in rabbit This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting 3042-SAB5700486100UL EA
Anti-Phospho-CTNNB1-S45 antibody produced in rabbit The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded 3042-SAB5700419100UL EA
Anti-Phospho-HNF4A-S304 antibody produced in rabbit The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the e 3042-SAB5700496100UL EA
Anti-Phospho-EphA3-Y779 antibody produced in rabbit This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typical 3042-SAB5700444100UL EA
Anti-Phospho-NEDD4L-S448 antibody produced in rabbit This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degrad 3042-SAB5700504100UL EA
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