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Anti-Spire1 antibody produced in rabbit Prestige Antibodies(R) Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

ITEM#: 3042-HPA040942100UL

MFR#: HPA040942-100UL

SPIRE1 (spire type actin nucleation factor 1) is a modular protein, that has a cluster of four actin-binding WH2 (wasp-homology 2) domains. It belongs to the SPIRE family of actin nucleators. The N-terminal region (Nt-Spire) comprises of a kinase-lik

SPIRE1 (spire type actin nucleation factor 1) is a modular protein, that has a cluster of four actin-binding WH2 (wasp-homology 2) domains. It belongs to the SPIRE family of actin nucleators. The N-terminal region (Nt-Spire) comprises of a kinase-like noncatalytic domain (KIND) and the C-terminal moiety has a spir box and a FYVE-related domain. Spire1 is expressed in cerebellum and cerebrum. This gene located on human chromosome 18p.