ITEM#: 3042-HPA040942100UL
MFR#: HPA040942-100UL
SPIRE1 (spire type actin nucleation factor 1) is a modular protein, that has a cluster of four actin-binding WH2 (wasp-homology 2) domains. It belongs to the SPIRE family of actin nucleators. The N-terminal region (Nt-Spire) comprises of a kinase-lik