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ITEM#: 3042-SMB009505MG
MFR#: SMB00950-5MG
O-Desmethyl gefitinib is a major active metabolite of gefitinib. It is a potent EGFR (erbB1/HER1) inhibitor (IC50 = 36 nM). Gefitinib is metabolized by CYP2D6 to O-Desmethyl gefitinib. Gefitinib is an EGFR inhibitor that is used to treat some types o
| Product Name | Description | Item# | QTY | |
|---|---|---|---|---|
N-Desmethyl imatinib >=95%
|
N-Desmethyl imatinib is a pharmacologically active metabolite of imatinib with long elimination half-life. Imatinib is metabolized to N-desmethyl imatinib by CYPs 3A4 and 2C8. | 3042-SMB0095825MG | EA | |
N-Desmethyl imatinib >=95%
|
N-Desmethyl imatinib is a pharmacologically active metabolite of imatinib with long elimination half-life. Imatinib is metabolized to N-desmethyl imatinib by CYPs 3A4 and 2C8. | 3042-SMB009585MG | EA | |
O-Desmethyl-cis-tramadol hydrochloride solution
|
O-Desmethyl-cis-tramadol hydrochloride solution | 3042-T0351ML | EA | |
O-Desmethyl-cis-tramadol-D6 hydrochloride solution
|
O-Desmethyl-cis-tramadol-D6 hydrochloride solution | 3042-D0581ML | EA | |
Gefitinib >=98% (HPLC)
|
Gefitinib >=98% (HPLC) | 3042-SML165710MG | EA |