OECM-1 Human Oral Squamous Carcinoma Cell Line

OECM-1 Human Oral Squamous Carcinoma Cell Line OECM-1 human oral squamous carcinoma cell line is suitable for studies of cancer cell signaling, epithelial-mesenchymal transition (EMT), metastasis, invasion, and cancer cell stemness. The OECM-1 human oral cavity squamous cell carcinoma cell line is a well-established model for squamous cell carcinoma. The OECM-1 cell line harbors a missense mutation in the p53 tumor suppressor , displays low EGFR expression , and is tumorigenic in nude mice . OECM-1 cells proliferate with a doubling time of 30-38 hours and are capable of anchorage-independent growth, forming spheroid colonies . OECM-1 cells have been intensively characterized in the literature for morphology, biomarker expression and drug response .Source:The OECM-1 human oral cavity squamous cell carcinoma cell line was derived from surgical resection of a primary tumor of a Taiwanese male patient .