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SILu(TM)Lite HAVCR1 Hepatitis A virus cellular receptor 1 human recombinant, expressed in HEK 293 cells, MS Protein Standard

ITEM#: 3042-MSST004250UG

MFR#: MSST0042-50UG

HAVCR1 is a trans-membrane glycoprotein that is highly expressed in kidney proximal tubular cells with kidney injury. The KIM-1 ectodomain is cleaved, released into urine, and canbe quantified as a sensitive and specific biomarker for Acute Kidney

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HAVCR1 is a trans-membrane glycoprotein that is highly expressed in kidney proximal tubular cells with kidney injury. The KIM-1 ectodomain is cleaved, released into urine, and canbe quantified as a sensitive and specific biomarker for Acute Kidney Injury (AKI) in rodents and humans. In a recent study it was demonstrated that HAVCR1 is released into the circulation where it reports kidney injury in mice, rats, and humans with AKI and chronic kidney disease (CKD). Urinary HAVCR1 and MCP-1 levels, either alone or in combination, were significantly higher than those in AKI negative patients. Importantly, the combination of HAVCR1 and MCP-1 outperformed either biomarker alone.
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Product Name Description Item# QTY
SILu(TM)Prot HAVCR1 Hepatitis A virus cellular receptor 1 human recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C and 15N-labeled HAVCR1 is a trans-membrane glycoprotein that is highly expressed in kidney proximal tubular cells with kidney injury. The KIM-1 ectodomain is cleaved, released into urine, and canbe quantified as a sensitive and specific biomarker for Acute Kidney In 3042-MSST004110UG EA
SILu(TM)Lite SOST, Sclerostin human recombinant, expressed in HEK 293 cells, MS Protein Standard SILu(TM)Lite SOST is a recombinant human protein expressed in human 293 cells. It consists of 201 amino acids (including a N-terminal polyhistidine and tag), with a calculated molecular mass of 22.8 kDa. SILu(TM)Lite SOST is an analytical standard de 3042-MSST004850UG EA
SILu(TM)Lite APOA1 Apolipoprotein A-1 human recombinant, expressed in HEK 293 cells, MS Protein Standard SILu(TM)Lite APOA1 Apolipoprotein A-1 human recombinant, expressed in HEK 293 cells, MS Protein Standard 3042-MSST000250UG EA
SILu(TM)Lite CLU Clusterin human recombinant, expressed in HEK 293 cells, MS Protein Standard SILu(TM)Lite Clusterin is a recombinant human protein expressed in human 293 cells. It is a heterodimer of 2 subunits (alpha and beta) consisting of 427 amino acids (including N-terminal polyhistidine and V5 tags), with a calculated molecular weight 3042-MSST000850UG EA
SILu(TM)Lite ALB Albumin human recombinant, expressed in HEK 293 cells, MS Protein Standard SILu(TM)Lite ALB is a recombinant human protein expressed in human 293 cells. It is a monomer of 607 amino acids (including C-terminal polyhistidine and flag tags), with a molecular weight of ~69 kDa. SILu(TM)Lite ALB is an analytical standard design 3042-MSST001250UG EA
SILu(TM)Lite APOA2 Apolipoprotein A-II human recombinant, expressed in HEK 293 cells, MS Protein Standard Apolipoprotein A-II (ApoA-II) occurs in plasma as a dimer of two 77-amino acid chains linked by a disulfide bridge. After apoA-I, it is the second major protein component of HDL, accounting for approximately 20% of HDL total protein. ApoA-II is thoug 3042-MSST003050UG EA
SILu(TM)Lite IL6 Interleukin 6 human recombinant, expressed in HEK 293 cells, MS protein standard SILu(TM) Lite IL-6 is a recombinant human protein expressed in human 293 cells. It is a monomer of 183 amino acids, with a molecular weight of ~21 kDa. SILu(TM) Lite IL-6 is an analytical standard designed to be used as starting material for preparat 3042-MSST001850UG EA
SILu(TM)Lite IL8, Interleukin-8 human recombinant, expressed in HEK 293 cells, MS Protein Standard SILu(TM)Lite IL8 is a recombinant human protein expressed in human 293 cells. It is a mixture of the 3 main CXCL8 isoforms with the molecular weights, amino acid number and relative abundance as described in Table 1 of the product datasheet. SILu(TM) 3042-MSST005850UG EA
SILu(TM)Lite IFNG Interferon Gamma human recombinant, expressed in HEK 293 cells, MS Protein Standard Interferon gamma (IFNgamma) is a dimerized soluble cytokine that is the only member of the type II class of interferons. IFNgamma is secreted by T helper cells (specifically, Th1 cells), cytotoxic T cells (TC cells) and Natural killer (NK) cells. Whe 3042-MSST004050UG EA
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