AlphaLISA Anti-Human IgG1 Acceptor Beads, 250 ug

AlphaLISA Acceptor beads conjugated to an anti-human IgG1. This bead can be used to create no-wash AlphaLISA assays for isotyping and other applications. This part is a replacement for AL153. Immunoglobulin G1 (IgG1) belongs to the immunoglobulin antibody family and is the most abundant IgG subclass. IgG molecules are created and released by plasma B cells and represent an important mediated antibody response against viral pathogens by binding to soluble proteins and membrane protein antigens via variable domain and concomitantly activating effector mechanisms of the innate immune system. IgG1 can bind to C1q, causing complement-dependent cytotoxicity (CDC), and can bind to each of the different Fc receptors resulting in antibody-dependent cell-mediated cytotoxicity (ADCC). Increased IgG1 levels have been associated with inflammatory or autoimmune diseases that involve the central nervous system and IgG1 deficiencies are associated with a weakened immune system and increased susc