AlphaLISA High Performance Human IL-2 Detection Kit, 5,000 Assay Points

The AlphaLISA High Performance (HP) Human IL-2 Detection Kit is designed for the quantitative determination of human IL-2 in serum, buffered solution, or cell culture medium using a homogeneous (no wash steps, no separation steps) assay. This kit is the new and improved version of part number AL221. Interleukin 2 (IL-2), formerly known as T-cell growth factor (TCGF), is a 15 kDa immunoregulatory lymphokine produced by lectin- or antigen-activated T cells and capable of inducing the thymic expansion of recently activated antigen-specific T lymphocytes. However, since T-cell immunity can be elicited to various agents in the absence of IL-2 in vivo, it is currently thought that the main non-redundant activity of this cytokine is the induction of the suppressor function of CD4+CD25+ regulatory T cells (Treg) in peripheral lymph nodes to ensure suppression of autoreactive T cells that escape negative selection. Moreover, studies suggest that IL-2-mediated regulation of Treg cells is im