AlphaLISA SureFire Ultra Human and Mouse Phospho-?;-Synuclein (Ser129) Detecti

The AlphaLISA SureFire Ultra Human and Mouse Phospho-?;-Synuclein (Ser129) assay is a sandwich immunoassay for quantitative detection of phospho-?;-Synuclein (Ser129) in cellular lysates using Alpha Technology. . ?;-Synuclein is a neuronal protein encoded by the SNCA gene that regulates synaptic vesicle trafficking and subsequent neurotransmitter release. ?;-Synuclein is a prominent component of intracellular fibrillary aggregates in the brains of patients suffering from synucleinopathies. This protein represents a key molecular hallmark for Parkinson's disease, dementia with Lewy bodies, or multiple system atrophy. The extensive phosphorylation of ?;-Synuclein on Ser129 is also associated with a pathological event. The AlphaLISA SureFire Human and Mouse Phospho-?;-Synuclein (Ser129) Detection Kit is a sandwich immunoassay for the quantitative detection of phosphorylated alpha synuclein in cellular lysates, using Alpha Technology. Formats The HV (high volume) kit contains