AlphaLISA SureFire Ultra Human and Mouse Total Androgen Receptor Detection Kit

The AlphaLISA SureFire Ultra Human and Mouse Total Androgen Receptor assay is a sandwich immunoassay for quantitative detection of total Androgen Receptor in cellular lysates using Alpha Technology. . Androgen Receptor (AR) is a type of nuclear receptor that is activated by androgen hormones, such as testosterone and dihydrotestosterone. Gene expression induced by AR results in cell division, proliferation, differentiation, apoptosis, and angiogenesis. Dysregulation of the AR pathway could lead to oncogenic phenotypes, and AR activation has been widely linked to prostate cancer as well as other types of cancer, like breast cancer and glioblastoma. The development of PROTAC compounds to target AR degradation is a part of the therapeutic strategy to target AR positive cancers. The AlphaLISA SureFire Human and Mouse Total Androgen Receptor Detection Kit is a sandwich immunoassay for the quantitative detection of total Androgen Receptor in cellular lysates, using Alpha Technolo