AlphaLISA SureFire Ultra Human and Mouse Total BRD2 Detection Kit, 500 Assay P

The AlphaLISA SureFire Ultra Human and Mouse Total BRD2 assay is a sandwich immunoassay for quantitative detection of total BRD2 in cellular lysates using Alpha Technology. Bromodomain containing 2 protein (BRD2) is a member of the Family II of Bromodomains, which includes BRD3 and BRD4. BRD2 is associated with transcription complexes and acetylated chromatin during mitosis and plays an important role in gene transcription. BRD2 and BRD3 perform overlapping cellular functions which suggests that the simultaneous disruption or depletion of these proteins may represent a promising drug therapeutic strategy against cancer. Dysregulation of BRD2 is linked to numerous cancers, such as breast, multiple myeloma, and acute leukemia. The AlphaLISA SureFire Human and Mouse Total BRD2 Detection Kit is a sandwich immunoassay for the quantitative detection of total BRD2 in cellular lysates, using Alpha Technology. Formats The HV (high volume) kit contains reagents to run 100 wells in