AlphaLISA SureFire Ultra Human and Mouse Total BRD7 Detection Kit, 500 Assay P

The AlphaLISA SureFire Ultra Human and Mouse Total BRD7 assay is a sandwich immunoassay for quantitative detection of total BRD7 in cellular lysates using Alpha Technology. Bromodomain containing 7 (BRD7), also known as NAG4, BP75, or CELTIX1, is a member of the Bromodomain-containing Protein Family IV, which also includes BRD9. BRD7 plays a role in chromatin remodeling and regulation of transcription. Inhibition of BRD7 expression promotes cell proliferation and migration by activating ERK phosphorylation. Increasing evidence indicates that BRD7 is downregulated in many cancers, such as epithelial ovarian carcinoma, breast cancer, nasopharyngeal cancer, and colorectal carcinoma. The AlphaLISA SureFire Human and Mouse Total BRD7 Detection Kit is a sandwich immunoassay for the quantitative detection of total BRD7 in cellular lysates, using Alpha Technology. Formats The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 (mu)L reaction vol