AlphaLISA SureFire Ultra Human and Mouse Total CDK9 Detection Kit, 500 Assay P

The AlphaLISA SureFire Ultra Human and Mouse Total CDK9 assay is a sandwich immunoassay for quantitative detection of total CDK9 in cellular lysates using Alpha Technology. . Cyclin dependent kinase 9 (CDK9) is a member of the CDK family. CDK9 was found to be a component of the multiprotein complex TAK/P-TEFb which regulates transcription elongation through phosphorylation of the C-terminal tail domain (CTD) of RNA polymerase II (RNAP II). This crucial function combined with evidence that transcriptional programs are dysregulated in cancer make CDK9 an attractive target for cancer therapies. The AlphaLISA SureFire Human and Mouse Total CDK9 Detection Kit is a sandwich immunoassay for the quantitative detection of total CDK9 in cellular lysates, using Alpha Technology. Formats The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 (mu)L reaction volume. The 500-point kit contains enough reagents to run 500 wells in 384-well format, using