AlphaLISA SureFire Ultra Human Phospho-NPM (Thr199) Detection Kit, 500 Assay P

The AlphaLISA SureFire Ultra Human Phospho-NPM (Thr199) assay is a sandwich immunoassay for quantitative detection of phospho-NPM (Thr199) in cellular lysates using Alpha Technology. . Nucleophosmin (NPM, Nucleolar Phosphoprotein B23, No38, or Numatrin) is a highly conserved, abundant nucleolar protein found in the nuclei of proliferating cells. NPM is a chaperone protein that shuttles rapidly between the nucleus and cytoplasm. It plays key roles in ribosome biogenesis, centrosome duplication, genomic stability, cell cycle progression, and apoptosis. NPM overexpression, mutation, rearrangement, or deletion, is associated with several types of cancer. The AlphaLISA SureFire Human Phospho-NPM (Thr199) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-NPM (Thr199) in cellular lysates, using Alpha Technology. Formats The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 (mu)L reaction volume. The 500-point ki