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Anti-CD169 antibody, Rabbit monoclonal clone SP213, recombinant, expressed in proprietary host, affinity isolated antibody

ITEM#: 3042-SAB5500043100UL

MFR#: SAB5500043-100UL

CD169 or sialoadhesin is a cell adhesion molecule on the surface of some macrophages distributed in the spleen, liver, lymph node, bone marrow, colon, lung, and various inflammatory tissues. It acts as an endocytic-receptor mediating clathrin-depende

CD169 or sialoadhesin is a cell adhesion molecule on the surface of some macrophages distributed in the spleen, liver, lymph node, bone marrow, colon, lung, and various inflammatory tissues. It acts as an endocytic-receptor mediating clathrin-dependent endocytosis. CD169 predominately binds to neutrophils, but can also bind to monocytes, natural killer cells, B cells and a subset of cytotoxic T cells by interacting with sialic acid molecules on their surfaces of their ligands.