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Anti-DVL1 (AB2) antibody produced in rabbit IgG fraction of antiserum

ITEM#: 3042-AV32101100UL

MFR#: AV32101-100UL

DVL1 is homologus to the Drosophila dishevelled gene and codes for a 670 amino acid protein. DVL1 comprises of three conserved domains: an N-terminal DIX domain, a central PDZ domain, and, lastly, a DEP domain. Overexpression of DVL1 has been linked

DVL1 is homologus to the Drosophila dishevelled gene and codes for a 670 amino acid protein. DVL1 comprises of three conserved domains: an N-terminal DIX domain, a central PDZ domain, and, lastly, a DEP domain. Overexpression of DVL1 has been linked to prostate and breast cancers through the Wnt signaling pathway. Rabbit Anti-DVL1 (AB1) antibody recognizes canine, human, mouse, rat, and bovine DVL1.