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ANTI-HIF1ALPHA(C-TERMINAL) antibody produced in rabbit purified immunoglobulin, buffered aqueous solution

ITEM#: 3042-SAB1306172400UL

MFR#: SAB1306172-400UL

Hypoxia-inducible factor-1 (HIF1) is a transcription factor expressed in mammalian cells when cultured under reduced oxygen tension. HIF1 is a heterodimer composed of an α subunit and a β subunit. The β subunit has been identified as the aryl hydr

Hypoxia-inducible factor-1 (HIF1) is a transcription factor expressed in mammalian cells when cultured under reduced oxygen tension. HIF1 is a heterodimer composed of an α subunit and a β subunit. The β subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. HIF-1α contains two transactivation domains. The gene encoding it is localized on human chromosome 14q23.2.