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Anti-MSH6 antibody, Rabbit monoclonal clone SP93, recombinant, expressed in proprietary host, affinity isolated antibody

ITEM#: 3042-SAB5500145100UL

MFR#: SAB5500145-100UL

Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predis

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Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.
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Product Name Description Item# QTY
Anti-CD1A antibody, Rabbit monoclonal clone SP157, recombinant, expressed in proprietary host, affinity isolated antibody T cell surface glycoprotein CD1a is a member of the CD1 family of transmembrane glycoproteins and a MHC Class 1 related cell surface glycoprotein involved in antigen processing and presentation. It forms heterodimers with beta 2-microglobulin. CD1a i 3042-SAB5500048100UL EA
Anti-Nucleophosmin antibody, Rabbit monoclonal clone SP236, recombinant, expressed in proprietary host, affinity isolated antibody The NPM1 (nucleophosmin 1) gene is mapped to human chromosome 5q35.1. Nucleophosmin is a predominant phospho-nucleolar protein, that is mostly, localized to the nucleus or cytoplasm. 3042-SAB5500154100UL EA
Anti-Vinculin antibody, Rabbit monoclonal clone SP117, recombinant, expressed in proprietary host, affinity isolated antibody Vinculin is a muscle-specific cytoskeletal protein associated with the cytoplasmic faces of both cell-cell and cell extracellular matrix adherens type junctions. It functions as one of several interacting proteins involved in anchoring F-actin to the 3042-SAB5500192100UL EA
Anti-CD21 antibody, Rabbit monoclonal clone SP186, recombinant, expressed in proprietary host, affinity isolated antibody CD21 antigen, also known as complement receptor type 2 (CR2), is a glycoprotein and a receptor for the C3d fragment of complement component 3. It is predominantly expressed in follicular dendritic cells and B lymphocytes. CD21 binds to CD19, and CD81 3042-SAB5500050100UL EA
Anti-EGFR antibody, Rabbit monoclonal clone SP111, recombinant, expressed in proprietary host, affinity isolated antibody EGFR is a transmembrane tyrosine kinase that belongs to the HER/erbB protein family. Somatic mutations in the tyrosine kinase domain of EGFR are present in a subset of lung adenocarcinoma. Two types of mutations account for approximately 90% of mutan 3042-SAB5500098100UL EA
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