EMAIL US: customerservice@franklinyoung.com
CALL US: (618) 724-2780 / (909) 931-5012
CALL US: (618) 724-2780 / (909) 931-5012
Back to Previous Page
ITEM#: 3042-SAB5500145100UL
MFR#: SAB5500145-100UL
Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predis
| Product Name | Description | Item# | QTY | |
|---|---|---|---|---|
Anti-CD43 antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP55, affinity isolated antibody
|
The SPN (sialophorin) gene is mapped to human chromosome 16p11.2 and encodesa transmembrane sialoglycoprotein cluster of differentiation 43 (CD43). It is localized to the surface of leukocytes and is expressed in hematopoietic cells. CD43 protein str | 3042-SAB5500067100UL | EA | |
Anti-SMA antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP171, affinity isolated antibody
|
Smooth muscle actin-α (SMA), also known as α2-smooth muscle actin (ACTA2), is a cytoskeleton protein in smooth muscle cells. It is encoded by the gene mapped to human chromosome 10q23.31. SMA is a vascular smooth muscle specific isoform, | 3042-SAB5500002100UL | EA | |
Anti-C4D antibody, Rabbit monoclonal clone SP91, recombinant, expressed in proprietary host, affinity isolated antibody
|
C4 plays a central role in the activation of the classical pathway of the complement system. Prior to secretion, the single-chain precursor is enzymatically cleaved to yield the non-identical chains (alpha, beta and gamma). During activation, the alp | 3042-SAB5500020100UL | EA | |
Anti-EZH2 antibody, Rabbit monoclonal clone SP129, recombinant, expressed in proprietary host, affinity isolated antibody
|
KMT6/Enhancer of zeste homologue 2 (EZH2) is a histone lysine methyl transferase associated with transcriptional repression. It is a component of the polycomb repressive complexes PRC2 and PRC3. The PRC2 complex catalyses histone H3 K27 trimethylatio | 3042-SAB5500102100UL | EA | |
Anti-MSH2 antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP46, affinity isolated antibody
|
MSH2 is involved in DNA repair as a mismatch repair protein, and mutations of MSH2 are found in approximately 50% of inherited non polyposis colorectal carcinoma (HNPCC) (Lynch syndrome) cases. HNPCC is an autosomal, dominantly inherited disease asso | 3042-SAB5500144100UL | EA |