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Anti-Septin-9 Antibody, clone 1A6C2 clone 1A6C2, from rat

ITEM#: 3042-MABT321

MFR#: MABT321

Septin-9 (also known as eighth septin, Eseptin, and MLL septin-like fusion) is encoded by the Sept9 gene in rat and mouse (SEPT9 in human). Septins are GTP-binding proteins capable of forming higher-order oligomers and filamentous polymers that conta

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Septin-9 (also known as eighth septin, Eseptin, and MLL septin-like fusion) is encoded by the Sept9 gene in rat and mouse (SEPT9 in human). Septins are GTP-binding proteins capable of forming higher-order oligomers and filamentous polymers that contact with the cell membrane and cytoskeleton. Septins are involved in various cellular processes, including cytokinesis, karyokinesis, exocytosis, and cell shape maintenance. The expression of SEPT2, SEPT6, SEPT7 and SEPT9 in heart tissue is reported to correlate well with cardiomyocyte cytokinesis activity during heart development, is highly expressed in embryonic heart, downregulated around birth, and nondetectable in the adult heart. (PMID 16739252 & 24837489). Clone 1A6C2 was generated using an immunogen sequence present only in rat spetin-9 isoform 1 (SLP-a; Q9QZR6), but missing in rat isoform 2-4 (SLP-b, E-septin long & short forms). The immunogen sequence is 100% conserved in murine species (A2A6U3) and differs by one amino acid when compared to the corresponding human sequence in isoform 2, and missing in human isoforms 1,3,4 (Q9UHD8).
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Product Name Description Item# QTY
Manufacturer Default Logo Monoclonal Anti-Septin 9 antibody produced in rat ~1.0 mg/mL, clone Clone 1A6C2 Monoclonal Anti-Septin 9 antibody produced in rat ~1.0 mg/mL, clone Clone 1A6C2 3042-SAB4200191200UL EA
Anti-Septin-3 Antibody, clone 5C1.2 clone 5C1.2, from mouse Neuronal-specific septin-3 (UniProt Q9UH03) is encoded by the SEPT3 (also known as SEP3) gene (Gene ID 55964) in human. Septins are GTPases capable of forming higher-order oligomers and filamentous polymers that contact with cell membrane and cytoske 3042-MABN1530 EA
Anti-Septin-6 Antibody, clone 9E7 clone 9E7, from mouse Septin-6 is a filament-forming GTPase that participates in cytokenisis and is necessary for the normal organization of the actin cytoskeleton. It is widely expressed in tissues and is found in the cytoplasm and in the spindle during metaphase. Four i 3042-051566 EA
Anti-Septin-9 Antibody, clone 10C10 clone 10C10, from mouse Septin-9 (UniProt Q9UHD8; also known as MLL septin-like fusion protein, MLL septin-like fusion protein MSF-A, Ovarian/Breast septin, Ov/Br septin, SeptD1, Septin D1) is encoded by the SEPT9 (also known as AF17q25, KIAA0991, MSF, MSF1, PNUTL4, SINT1) 3042-MABE992 EA
Anti-Microsialin/CD68 Antibody, clone 9 clone 9, 1 mg/mL, from rat Microsialin/CD68, also known as Macrosialin, Gp110, CD_antigen 68, or CD68, and encoded by the gene CD68, is a membrane protein expressed in macrophages (and other cells) that appears to play a role in the phagocytic activities of tissue macrophages 3042-MABF216 EA
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