BioTracker Green Copper Live Cell Dye Live Cell imaging probe for detection of Copper (Cu+) ion in live cells.

Copper is one of the trace metals required by living organisms and is an essential cofactor for enzyme activities of cytochrome c oxidase, superoxide dismutase, and tyrosinase. On the other hand, abnormal homeostasis of copper leads to severe disorders such as Menkes syndrome and Wilson's disease, or may be related to Alzheimer's disease and cancers.BioTracker Green Copper Live Cell Dye is a fluorescent probe to detect Cu+, which is a dominant redox state of copper in an intracellular reducing environment. The dye is a colorless material with almost no fluorescence. Upon the reaction with Cu+, its fluorescence intensity at 510 nm increases more than 100 times to that before the reaction. However, fluorescence increase is not observed in the presence of reactive oxygen species and other trace metals in cells including Cu2+, Mn2+, Co2+, Ni2+, Fe+, Fe2+ and Zn2+.Spectral Properties:Absorbance (max): 480nmEmission (max): 510nmResearch Category:Live Cell Dye