Monoclonal Anti-alpha-Actinin antibody produced in mouse clone BM-75.2, ascites fluid

alpha-actinin is a 100kD actin binding protein found in muscle as well as non-muscle cells. In smooth muscle, alpha-actinin is identified in dense bodies and plaques characteristic of tissues whereas it is associated with z-discs that define muscle sarcomas in normal skeletal muscle. Monoclonal anti-alpha-actinin antibody can be used in immunoblotting to study the membrane anchorage sites and immunochemical identification of alpha-actinin. It can also be used in immunofluorescence to study the localization of alpha-actinin in cultured cells and tissues. Mouse anti-alpha-actinin antibody reacts specifically with chicken fibroblasts. The product has also shown reactivity for mouse and human cells.