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Polymyxin B ready made solution Cell culture tested, 17 mg/mL in H2O, 0.2 mum filtered

ITEM#: 3042-P11895ML

MFR#: P1189-5ML

Polymyxin B (PMB) is a cyclic cationic lipopeptide antibiotic originally produced by soil bacterium Bacillus polymyxa. Polymyxin B binds specifically to gram negative bacteria by interacting with the anionic lipopolysaccharide (LPS, or endotoxin). Po

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Polymyxin B (PMB) is a cyclic cationic lipopeptide antibiotic originally produced by soil bacterium Bacillus polymyxa. Polymyxin B binds specifically to gram negative bacteria by interacting with the anionic lipopolysaccharide (LPS, or endotoxin). Polymyxin B interferes with the outer membrane normal function causing leakage and enhanced uptake of the antibiotic.Polymyxin B has several applications:. It is used to neutralize LPS contamination in vitro and in vivo. Its neutralizing effect is dose-dependent. In vitro experiments showed that PMB inhibits a septic shock by endotoxin inactivation. Cell cultures can be treated with PMB (100U/mL) to avoid early contaminations. PMB is considered a broad spectrum antibiotic and is used to treat infections caused by bacteria resistant to a combination of Penicillin and Streptomycin. PMB is also used as negative and positive control in minimum microbicidal concentration (MIC) assay. Working concentration:The suggested concentration of PMB in cell culture mediums is 100U/mL. Therefore, it is recommended to dilute PMB ready made solution 1:1000.
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Product Name Description Item# QTY
Polymyxin B ready made solution Cell culture tested, 17 mg/mL in H2O, 0.2 mum filtered Polymyxin B (PMB) is a cyclic cationic lipopeptide antibiotic originally produced by soil bacterium Bacillus polymyxa. Polymyxin B binds specifically to gram negative bacteria by interacting with the anionic lipopolysaccharide (LPS, or endotoxin). Po 3042-P11891ML EA
Bleomycin ready made solution Cell culture tested, 10 mg/mL in H2O, 0.2 mum filtered Bleomycin (BLM) is a glycopeptide antibiotic consist of 2 main isomers, BLM A2 and B2, obtained from Streptomyces verticillus. The main clinical application of Bleomycin is cancer treatment. Bleomycin causes oxidative degradation of RNA affecting G2 3042-B72161ML EA
Spectinomycin ready made solution 100 mg/mL in DMSO/H2O, 1:1, 0.2 mum filtered, Cell culture tested Spectinomycin is an aminocyclitol antibiotic naturally produced by Streptomyces spectabilis. Spectinomycin shows in vitro inhibitory effect (31.2(mu)g/mL) against gram-negative and gram-positive bacteria like Escherichia coli, Klebsiella, Enterobacte 3042-S62581ML EA
Mitomycin C ready made solution 10 mg/mL in DMSO, 0.2 mum filtered, >=98% (HPLC), Cell culture tested Mitomycin C ready made solution 10 mg/mL in DMSO, 0.2 mum filtered, >=98% (HPLC), Cell culture tested 3042-M53535X02ML EA
Puromycin ready made solution 10 mg/mL in H2O, 0.2 mum filtered, >=98% (HPLC), Cell culture tested Puromycin ready made solution 10 mg/mL in H2O, 0.2 mum filtered, >=98% (HPLC), Cell culture tested 3042-P45121MLX10 EA
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