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Porcine Aortic Smooth Muscle Cells: PAOSMC (Cryovial)

ITEM#: 3042-P35405

MFR#: P354-05

PAOSMC were used to investigate the effects of heparin on smooth muscle cell proliferation, specifically revealing that heparin induces MKP-1 phosphatase that dephosphorylates ERK, decreasing its activity (Blaukovitch, 2010). They were also used to s

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PAOSMC were used to investigate the effects of heparin on smooth muscle cell proliferation, specifically revealing that heparin induces MKP-1 phosphatase that dephosphorylates ERK, decreasing its activity (Blaukovitch, 2010). They were also used to show that normalization of myocardin signaling in the diseased heart by using targeted inhibition of myocardin genes by shRNA restores heart function (Torrado, 2011). Finally, PAOSMC along with Porcine Aortic Endothelial cells, have been used as controls in a study characterizing circulating endothelial progenitor cells (Allen, 2008).Characterization: positive for smooth muscle cell specific alpha-actin expression.
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Product Name Description Item# QTY
Rabbit Aortic Smooth Muscle Cells: RbAOSMC (Cryovial) RbAOSMC from Cell Applications, Inc. were used to demonstrate that anti-restenosis drug probucol inhibition of vascular smooth cell proliferation by enhancing apoptosis and inducing heme oxygenase-1 (Deng, 2004). RbAOSMC were also used to evaluate pe 3042-RB35405 EA
Canine Aortic Smooth Muscle Cells: CnAOSMC (Cryovial) Canine Aortic Smooth Muscle Cells (CnAOSMC) are derived from tunica intima and tunica media of normal canine aorta. They are cryopreserved at second passage and can be cultured and propagated at least 10 population doublings. Platelet-derived growth 3042-CN35405 EA
Bovine Aortic Smooth Muscle Cells: BAOSMC (Cryovial) Bovine large artery smooth muscle cells (BAOSMC) provide an excellent model system to study all aspects of cardiovascular function and disease, especially those related to mechanisms of hyperplasia and hypertrophy of intimal smooth muscle cells leadi 3042-B35405 EA
Porcine Coronary Artery Smooth Muscle Cells: PCASMC (Cryovial) PCASMC were used to investigate the role of c-Jun in smooth muscle proliferation, and to show that c-Jun inhibition abrogates smooth muscle cell growth and intimal thickening after arterial injury (Khachigian, 2002). PCASMC were also used to develop 3042-P35005 EA
Porcine Pulmonary Artery Smooth Muscle Cells: PPASMC (Cryovial) Porcine Pulmonary Artery Smooth Muscle Cells (PPASMC) provide a useful in vitro model to study cellular and molecular mechanisms of pulmonary hypertension characterized by hyperproliferation of pulmonary artery smooth muscle cells.Characterization: p 3042-P35205 EA
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