SDF-1alpha/CXCL2 from rat recombinant, expressed in E. coli, >=98% (SDS-PAGE)

SDF-1 (stromal-derived factor 1) is a constitutive gene which is ubiquitously expressed in vertebrate tissues. It was first identified in rat bone marrow (BM) stromal cell line supporting hematopoietic cell culture. This gene is regulated at splicing level, rather than transcriptional level and is spliced into multiple variants. Among these, SDF-1α is the major isoform expressed in all tissues, but is rapidly proteolysed in blood. This isoform is composed of 89 amino acids. SDF-1 is a member of the intercrine cytokine family or chemokine family of proteins, which are characterized by four conserved cysteines that form two disulfide bonds.Recombinant rat SDF-1α is a 7.9kDa protein containing 68 amino acid residues.