AlphaLISA SureFire Ultra Human and Mouse Phospho-SLP76 (Tyr145) Detection Kit,

The AlphaLISA SureFire Ultra Human and Mouse Phospho-SLP76 (Tyr145) assay is a sandwich immunoassay for quantitative detection of phopho-SLP76 (Tyr145) in cellular lysates using Alpha Technology. . Lymphocyte cytosolic protein 2 (SLP76) is a signal-transducing adaptor protein encoded by LCP2. This protein acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. Activated SLP76 translocates to the plasma membrane and promotes a multi-protein complex which participates in the activation, survival, and proliferation of T-Lymphocytes. SLP76 is associated with numerous therapeutic areas, including diseases such as multiple sclerosis, rheumatoid arthritis, psoriasis, and cancer. The AlphaLISA SureFire Human and Mouse Phospho-SLP76 (Tyr145) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-SLP76 (Tyr145) in cellular lysates, using Alpha Technology. Formats The HV (high volume) kit contains reagents to run