AlphaLISA SureFire Ultra Human Phospho-DAP12 (Tyr91) Detection Kit, 10,000 Ass

The AlphaLISA SureFire Ultra Human Phospho-DAP12 (Tyr91) assay is a sandwich immunoassay for quantitative detection of phospho-DAP12 (Tyr91) in cellular lysates using Alpha Technology. . DAP12, also known as TYRO protein tyrosine kinase-binding protein, functions as a signaling adapter for a number of innate immune system cell surface receptors. By activating SYK or Zap-70 and other downstream targets, crosslinking receptors linked to DAP12 causes tyrosine residues in their cytoplasmic ITAM to be phosphorylated by SRC family kinases, which initiates downstream signaling. By monitoring the neuronal surroundings and preserving a healthy brain homeostasis in microglia cells, the TREM2-DAP12 receptor complex seems to play an ongoing role. The AlphaLISA SureFire Human Phospho-DAP12 (Tyr91) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-DAP12 (Tyr91) in cellular lysates, using Alpha Technology. Formats: The HV (high volume) kit contains reagen