AlphaLISA SureFire Ultra Human Total TREM2/DAP12 Complex Detection Kit, 50,000

The AlphaLISA SureFire Ultra Human Total TREM2/DAP12 Complex assay is a sandwich immunoassay for quantitative detection of total TREM2/DAP12 Complex in cellular lysates using Alpha Technology. The TREM-2 (Triggering Receptor Expressed on Myeloid Cells 2) family of receptors regulates the immune system's various cell types, such as neutrophils, monocyte/macrophages, microglia, and dendritic cells. TREM-2 requires the adaptor protein DAP12 for downstream signaling. Human cerebrospinal fluid (CSF) has been shown to include soluble TREM-2, which has been reported to be increased in people with multiple sclerosis and other inflammatory neurological illnesses compared to those without such conditions. The AlphaLISA SureFire Human Total TREM2/DAP12 Complex is a sandwich immunoassay for the quantitative detection of total TREM2/DAP12 complex in cellular lysates, using Alpha Technology. Formats: The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using