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HTRF Human and Mouse Total CDK5 Detection Kit, 500 Assay Points

ITEM#: 2013-64CDK5TPEG KT

MFR#: 64CDK5TPEG

The Total CDK5 kit is designed to monitor the expression level of cellular CDK5 (Cyclin-Dependent Kinase 5). Cdk5 belongs to Cyclin-dependent kinases (Cdks) family. Despite having a high sequence homology with other members of Cdks family, CDK5 is a

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The Total CDK5 kit is designed to monitor the expression level of cellular CDK5 (Cyclin-Dependent Kinase 5). Cdk5 belongs to Cyclin-dependent kinases (Cdks) family. Despite having a high sequence homology with other members of Cdks family, CDK5 is an unusual member because its not directly involved in the regulation of the cell cycle and its activation does not require the phosphorylation state or binding with a cyclin. CDK5 represents an attractive pharmacological target as its dysregulation is implicated in various neurodegenerative diseases such as Alzheimer's, Parkinson's and various types of cancers.
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