HTRF Human and Mouse Total HDAC5 Detection Kit, 500 Assay Points

The Total HDAC5 kit is designed to monitor the expression level of cellular human and mouse HDAC5 and can be used as a normalization assay for the Phospho-Human HDAC5 Ser259 Detection Kit. Histone deacetylases (HDACs) regulate chromatin remodeling and subsequent gene transcription by controlling the status of histone acetylation. Histone deacetylation induces a condensed chromatin conformation, contributing to the repression of gene transcription, which is involved in diverse physiological processes. HDAC5 belongs to class IIa HDACs, including HDAC4, HDAC7 and HDAC9. It plays a key role in the control of cellular proliferation, differentiation, migration, apoptosis and metabolism.