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MDA5 aggregation kit, 10000 Tests

ITEM#: 2013-63ADK111PEH KT

MFR#: 63ADK111PEH

The MDA5 aggregation kit is designed for the fast detection of MDA5 aggregates in cell supernatants..MDA-5 is an RIG-I-like receptor that acts as a cytoplasmic sensor of double stranded RNA, and plays a major role in sensing viral infection and in th

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The MDA5 aggregation kit is designed for the fast detection of MDA5 aggregates in cell supernatants..MDA-5 is an RIG-I-like receptor that acts as a cytoplasmic sensor of double stranded RNA, and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. It is understood to form aggregates along RNA strands when performing its nucleic acid sensing functions. It may also play an important role in enhancing natural killer cell function, and may be involved in growth inhibition and apoptosis in several tumor cell lines..