Stable, recombinant AequoScreen cell line expressing aequorin and the Succinate receptor 1 (SUCNR1, GPR91), human recombinant in CHO-K1 host cells. Revvity's AequoScreen double transfected cell lines are provided in two vials of frozen cells, each containing ~2.5 x 10 cells. Detailed product information as well as recommended cell culture conditions and validation assay date are available each cell line. AequoScreen technology is a generic GPCR technology that can be used with G s , G i , and G q -coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of resulting flash luminescence signal. Features: Fully automatable and miniaturizable to 1536 Enables reduction in reagents and consumable costs High signal to background ratio enabling detection of agonists, antagonists and allosteric modulators Robust assay (Z′, CV values, solvent resistance) Reduces number of false pos
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