Anti-Syntaxin antibody, Mouse monoclonal clone HPC-1, purified from hybridoma cell culture

Syntaxins are a family of membrane-integrated proteins that are instrumental in exocytosis of vesicles.6 The syntaxin family consists of 15 genes in mammals and 7 in yeast, and there are syntaxin-like sequences in all eukaryotes examined.7 All mammalian syntaxins, with the exception of syntaxin 11, are transmembrane proteins anchored by their C-terminal tails.7 Syntaxin-1(also known as HPC-1 antigen or Stx1),8-9 a 35 kDa molecule with carboxyl-terminal membrane anchor, is a synaptic protein identified by its ability to interact with the synaptic vesicle protein synaptotagmin