ITEM#: 3042-SMB0092910MG
MFR#: SMB00929-10MG
Carvedilol is a beta- and alpha1-adrenoreceptor blocker for the treatment of hypertension and congestive heart failure (CHF). The drug is metabolized by CYP2D6 (to 4'-OH and 5'-OH), CYP2C9 (to O-desmethyl), CYP1A2 (to 8-OH). It is also oxidized to 1-