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ITEM#: 3042-SAB5500040100UL
MFR#: SAB5500040-100UL
Cluster of differentiation 14 (CD14) is a cell surface glycoprotein expressed on monocytes and macrophages. It cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). It is also involved in NF-kappa-
| Product Name | Description | Item# | QTY | |
|---|---|---|---|---|
Anti-CD43 antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP55, affinity isolated antibody
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The SPN (sialophorin) gene is mapped to human chromosome 16p11.2 and encodesa transmembrane sialoglycoprotein cluster of differentiation 43 (CD43). It is localized to the surface of leukocytes and is expressed in hematopoietic cells. CD43 protein str | 3042-SAB5500067100UL | EA | |
Anti-EZH2 antibody, Rabbit monoclonal clone SP129, recombinant, expressed in proprietary host, affinity isolated antibody
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KMT6/Enhancer of zeste homologue 2 (EZH2) is a histone lysine methyl transferase associated with transcriptional repression. It is a component of the polycomb repressive complexes PRC2 and PRC3. The PRC2 complex catalyses histone H3 K27 trimethylatio | 3042-SAB5500102100UL | EA | |
Anti-MSH2 antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP46, affinity isolated antibody
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MSH2 is involved in DNA repair as a mismatch repair protein, and mutations of MSH2 are found in approximately 50% of inherited non polyposis colorectal carcinoma (HNPCC) (Lynch syndrome) cases. HNPCC is an autosomal, dominantly inherited disease asso | 3042-SAB5500144100UL | EA | |
Anti-CD4 antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP35, affinity isolated antibody
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CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of | 3042-SAB5500064100UL | EA | |
Anti-PTEN antibody, Rabbit monoclonal clone SP218, recombinant, expressed in proprietary host, affinity isolated antibody
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The defects of PTEN have been implicated in human cancers from breast, prostate, thyroid, skin, endometrium, head and neck, and brain. Up to 50-60 percent of advanced prostate cancers show abnormal PTEN gene expression or loss of protein expression. | 3042-SAB5500169100UL | EA |