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ITEM#: 3042-SAB5500084100UL
MFR#: SAB5500084-100UL
Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and can be cleaved by caspase-3 at multiple sites (D301, D371, D375, and D384) during apoptosis. The generation of cleaved
| Product Name | Description | Item# | QTY | |
|---|---|---|---|---|
Anti-PTEN antibody, Rabbit monoclonal clone SP218, recombinant, expressed in proprietary host, affinity isolated antibody
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The defects of PTEN have been implicated in human cancers from breast, prostate, thyroid, skin, endometrium, head and neck, and brain. Up to 50-60 percent of advanced prostate cancers show abnormal PTEN gene expression or loss of protein expression. | 3042-SAB5500169100UL | EA | |
Anti-PTEN antibody, Rabbit monoclonal clone SP170, recombinant, expressed in proprietary host, affinity isolated antibody
|
Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and a member in the PI3K/PTEN/AKT pathway. PTEN is a phosphatase with dual specificity to slow cell growth and antagonize t | 3042-SAB5500168100UL | EA | |
Anti-SPINK1 antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP166, affinity isolated antibody
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Spink1 is a trypsin inhibitor secreted from pancreatic acinar cells into pancreatic juice. It prevents the trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Spink-1 is overexpressed in some prostate carci | 3042-SAB5500177100UL | EA | |
Anti-CD138 antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP152, affinity isolated antibody
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CD138 / Syndecan-1, is a transmembrane, heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycans. CD138 is expected to play a role in cell adhesion, cell proliferation, cell migration and cell-matrix interactions | 3042-SAB5500039100UL | EA | |
Anti-MSH6 antibody, Rabbit monoclonal clone SP93, recombinant, expressed in proprietary host, affinity isolated antibody
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Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predis | 3042-SAB5500145100UL | EA |