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ITEM#: 3042-AV34318100UL
MFR#: AV34318-100UL
CNOT3 is a subunit of the CCR4-NOT transcription complex. This subunit can bind to the PRPF31 promoter and mediate transcriptional repression. It acts as a modifier gene and controls the effects of PRPF31 mutations in retinitis pigmentosa. CNOT3 muta