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Anti-EGFR antibody, Rabbit monoclonal clone SP111, recombinant, expressed in proprietary host, affinity isolated antibody

ITEM#: 3042-SAB5500098100UL

MFR#: SAB5500098-100UL

EGFR is a transmembrane tyrosine kinase that belongs to the HER/erbB protein family. Somatic mutations in the tyrosine kinase domain of EGFR are present in a subset of lung adenocarcinoma. Two types of mutations account for approximately 90% of mutan

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EGFR is a transmembrane tyrosine kinase that belongs to the HER/erbB protein family. Somatic mutations in the tyrosine kinase domain of EGFR are present in a subset of lung adenocarcinoma. Two types of mutations account for approximately 90% of mutant cases: a specific point mutation L858R which occurs in exon 21 and short in-frame deletions in exon 19. A common lesion in exon 19 is the deletion of E746-A750, although other variants can also occur.
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Product Name Description Item# QTY
Anti-EGFR antibody, Rabbit monoclonal clone SP125, recombinant, expressed in proprietary host, affinity isolated antibody EGFR is a transmembrane tyrosine kinase of HER/erbB protein family. EGFR somatic mutations such as L858R in exon 21 and short in-frame deletion of E746-A750 in exon 19 are present in a subset of lung adenocarcinoma. 3042-SAB5500099100UL EA
Anti-EGFR antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP84, affinity isolated antibody Epidermal Growth Factor Receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophag 3042-SAB5500096100UL EA
Anti-CD22 antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP104, affinity isolated antibody CD22 is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140kD. It is expressed in both the cytoplasm and cell membrane of B lymphocytes. CD22 antigen appears early in B cell lymphocyte differentiation at approximately the same 3042-SAB5500052100UL EA
Anti-CDX2 antibody, Rabbit monoclonal clone SP54, recombinant, expressed in proprietary host, affinity isolated antibody CDX2 is a caudal type homeobox gene that encodes an intenstine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. 3042-SAB5500078100UL EA
Anti-C4D antibody, Rabbit monoclonal clone SP91, recombinant, expressed in proprietary host, affinity isolated antibody C4 plays a central role in the activation of the classical pathway of the complement system. Prior to secretion, the single-chain precursor is enzymatically cleaved to yield the non-identical chains (alpha, beta and gamma). During activation, the alp 3042-SAB5500020100UL EA
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