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ITEM#: 3042-SAB5500168100UL
MFR#: SAB5500168-100UL
Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and a member in the PI3K/PTEN/AKT pathway. PTEN is a phosphatase with dual specificity to slow cell growth and antagonize t
| Product Name | Description | Item# | QTY | |
|---|---|---|---|---|
Anti-PTEN antibody, Rabbit monoclonal clone SP218, recombinant, expressed in proprietary host, affinity isolated antibody
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The defects of PTEN have been implicated in human cancers from breast, prostate, thyroid, skin, endometrium, head and neck, and brain. Up to 50-60 percent of advanced prostate cancers show abnormal PTEN gene expression or loss of protein expression. | 3042-SAB5500169100UL | EA | |
Anti-Cleaved PTEN antibody, Rabbit monoclonal clone SP227, recombinant, expressed in proprietary host, affinity isolated antibody
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Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and can be cleaved by caspase-3 at multiple sites (D301, D371, D375, and D384) during apoptosis. The generation of cleaved | 3042-SAB5500084100UL | EA | |
Anti-CD20 antibody, Rabbit monoclonal clone SP32, recombinant, expressed in proprietary host, affinity isolated antibody
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CD20 is a 33kDa leukocyte surface antigen consisting of four transmembrane regions and cytoplasmic N- and C-termini. CD20 is expressed primarily on B cells but has also been detected on both normal and neoplastic T cells. Activation of CD20 significa | 3042-SAB5500049100UL | EA | |
Anti-CD21 antibody, Rabbit monoclonal clone SP186, recombinant, expressed in proprietary host, affinity isolated antibody
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CD21 antigen, also known as complement receptor type 2 (CR2), is a glycoprotein and a receptor for the C3d fragment of complement component 3. It is predominantly expressed in follicular dendritic cells and B lymphocytes. CD21 binds to CD19, and CD81 | 3042-SAB5500050100UL | EA | |
Anti-FOXP1 antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP133, affinity isolated antibody
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Forkhead box protein P1 (FOXP1) is a transcriptional repressor that plays an important role in the development of the brain and lung in mammals. The gene encoding this protein may act as a tumor suppressor as it is lost in several tumor types and map | 3042-SAB5500108100UL | EA |