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ITEM#: 3042-SAB5500169100UL
MFR#: SAB5500169-100UL
The defects of PTEN have been implicated in human cancers from breast, prostate, thyroid, skin, endometrium, head and neck, and brain. Up to 50-60 percent of advanced prostate cancers show abnormal PTEN gene expression or loss of protein expression.
| Product Name | Description | Item# | QTY | |
|---|---|---|---|---|
Anti-PTEN antibody, Rabbit monoclonal clone SP170, recombinant, expressed in proprietary host, affinity isolated antibody
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Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and a member in the PI3K/PTEN/AKT pathway. PTEN is a phosphatase with dual specificity to slow cell growth and antagonize t | 3042-SAB5500168100UL | EA | |
Anti-Cleaved PTEN antibody, Rabbit monoclonal clone SP227, recombinant, expressed in proprietary host, affinity isolated antibody
|
Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and can be cleaved by caspase-3 at multiple sites (D301, D371, D375, and D384) during apoptosis. The generation of cleaved | 3042-SAB5500084100UL | EA | |
Anti-Stathmin antibody, Rabbit monoclonal clone SP49, recombinant, expressed in proprietary host, affinity isolated antibody
|
Stathmin is a ubiquitous cyotsolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by desta | 3042-SAB5500178100UL | EA | |
Anti-CD1A antibody, Rabbit monoclonal clone SP157, recombinant, expressed in proprietary host, affinity isolated antibody
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T cell surface glycoprotein CD1a is a member of the CD1 family of transmembrane glycoproteins and a MHC Class 1 related cell surface glycoprotein involved in antigen processing and presentation. It forms heterodimers with beta 2-microglobulin. CD1a i | 3042-SAB5500048100UL | EA | |
Anti-KU80 antibody, Rabbit monoclonal recombinant, expressed in proprietary host, clone SP130, affinity isolated antibody
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X-ray repair cross-complementing protein 5 (XRCC5), alternative name (Ku80), is single stranded DNA-dependent ATP-dependent helicase. It involves in chromosome translocation. Ku80 along with Ku70 forms a heterodimeric protein originally identified as | 3042-SAB5500135100UL | EA |