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ITEM#: 2946-63485
MFR#: 6348/5
PF 06424439, potent selective DGAT2 inhibitor (IC50=14 nM), no MGAT1-3 or DGAT1 activity, reduces triglyceride synthesis in vitro, lowers plasma triglyceride/cholesterol in rat model, orally bioavailable, 5 MG, Tocris Bioscience, Assay Percent Range:
| Product Name | Description | Item# | QTY | |
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CP 673451, potent selective PDGFR inhibitor, 10mg, Tocris Bioscience
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CP 673451, potent and selective PDGFR inhibitor, IC50 1 and 10 nM, selective over related kinases, inhibits PDGFR- phosphorylation in glioblastoma xenografts, purity >98%, molecular formula C24H27N5O2, formula weight 417.5, 10mg, Tocris Bioscience | 2946-599310 | EA | |
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Torin 1, potent selective mTOR inhibitor, 50mg, Tocris Bioscience
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Torin 1, potent ATP-competitive mTOR inhibitor (IC50 2-10 nM), 200-fold selectivity for mTOR, induces autophagy in HeLa cells, 50mg, >98% purity, Molecular Weight: 607.637, CAS: 1222998-36-8, Tocris Bioscience | 2946-424750 | EA | |
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Torin 1, potent and selective mTOR inhibitor, 10mg, Tocris Bioscience
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Torin 1, ATP-competitive mTOR inhibitor, IC50 = 2-10 nM for mTORC1/mTORC2, 200-fold selectivity over DNA-PK, ATM, hVps34, induces autophagy, 10mg, >98% purity, CAS: 1222998-36-8, Tocris Bioscience | 2946-424710 | EA | |
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YNT 185, potent selective OX2 agonist, 10 mg, Tocris Bioscience
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YNT 185, potent selective OX2 agonist, EC50 28 nM OX2, 100-fold selectivity over OX1, depolarizes OX2-expressing histaminergic neurons, increases wake time in wild type mice, 10 mg | 2946-673910 | EA | |
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XAV 939, potent tankyrase inhibitor, 10mg, Tocris Bioscience
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XAV 939, potent tankyrase inhibitor, 10mg, IC50: 4 nM (TNKS2), 11 nM (TNKS1), purity >98%, CAS: 284028-89-3, antagonizes Wnt signaling, promotes cardiomyocyte and neuronal differentiation | 2946-374810 | EA |