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AC 187, potent amylin receptor antagonist, 500ug, Tocris Bioscience

ITEM#: 2946-3419500U

MFR#: 3419/500U

AC 187, potent orally active amylin receptor antagonist (IC50=0.48 nM). 38-fold and 400-fold selectivity over calcitonin and CGRP. Blocks amyloid-induced neurotoxicity in vitro; affects glucagon, gastric emptying, plasma glucose, food intake in vivo.

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AC 187, potent orally active amylin receptor antagonist (IC50=0.48 nM). 38-fold and 400-fold selectivity over calcitonin and CGRP. Blocks amyloid-induced neurotoxicity in vitro; affects glucagon, gastric emptying, plasma glucose, food intake in vivo.
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